Challenges : EMDataResource

EMDataResource Challenges

This page serves as a summary archive of the EMDataResource team's interactions with the 3DEM community to establish data validation methods for Cryo-EM structures. Following recommendations of the EM Validation Task Force (Henderson et al 2012), EMDR hosted and organized the Challenge activities listed below. Links are provided to publications and special journal issues as well as Zenodo-hosted Challenge data archives.

Participants in the 2017 CryoEM Structure Joint Challenges Workshop. — October 6-8, 2017 CryoEM Structure Joint Challenges Workshop. SLAC Campus, Stanford University, California.

2021 Ligand Model Challenge

Summary Publication (peer reviewed): Outcomes of the EMDataResource Cryo-EM Ligand Modeling Challenge. Nat Methods 21, 1340-1348 (2024). doi
Summary Publication (preprint version): Outcomes of the EMDataResource Cryo-EM Ligand Modeling Challenge.
Archived Data: 2021 EMDataResource Ligand Model Challenge Dataset
Interactive Data Tables/Plots: 2021 Model Challenge
Wrap-Up Workshop: Agenda and Documents

2019 Model Metrics Challenge

Summary Publication: Cryo-EM model validation recommendations based on outcomes of the 2019 EMDataResource challenge Nat Methods. 2021 Feb;18(2):156-164. Epub 2021 Feb 4. doi
Archived Data: 2019 EMDataResource Model Metrics Challenge Dataset
Interactive Data Tables/Plots: 2019 Model Challenge
Wrap-Up Workshop: Agenda and Documents

2016 Map & Model Challenges

Journal Special Issue: CryoEM Challenges Journal of Structural Biology (2018--19 articles)
Editorial Overview: Comparing cryo-EM structures. J Struct Biol. 2018 Oct 13. pii: S1047-8477(18)30277-6. doi
Data Processing: Distribution of evaluation scores for the models submitted to the second cryo-EM model challenge. Data Brief. 2018 Sep 8;20:1629-1638. doi
Archived Data: CryoEM Models and Associated Data Submitted to the 2015/2016 EMDataBank Model Challenge
Archived Data: CryoEM Maps and Associated Data Submitted to the 2015/2016 EMDataBank Map Challenge
Interactive Data Tables/Plots: 2016 Model Challenge
Wrap-Up Workshop: Agenda and Documents

2010 Model Challenge

Journal Special Issue: Biopolymers Vol 97, Issue 9: The 2010 Cryo-EM Modeling Challenge (9 articles)
Editorial Overview: The 2010 cryo-EM modeling challenge. Biopolymers. 2012 Sep;97(9):651-4. doi